Monday, July 30, 2007
alternate medicine
Why isnt this type of promising research followed up by those entities that claim to want prevent or cure AD? This brings me to a true story. The husband of a close friend, Mary, was diagnosed with Parkinsons disease. In the early stage, he had some hand tremor but what was most disturbing to Mary was evidence of cognitive decline. A math whiz, her husband now had difficulty with simple arithmetic. The doctor said medication was not yet indicated. He could offer nothing to help the cognitive problem. Mary asked if I knew anything that might help. I had recently seen research that showed progression of Parkinsons could be slowed a staggering 44 percent by taking 1,200 mg. of CoQ10 a day. (Normal daily dose is 50-150 mg). The Life Extension Foundation protocol for treatment of Parkinsons indicates up to 3,000 mg daily. There are no known side effects or contraindications for high doses of CoQ10. Mary started her husband on 1,200 mg a day and about two weeks later bumped up the dose up to 2,400 mg. Within a month, her husbands cognition was almost back to normal. Was it luck? Was it a miracle that would have occurred without the CoQ10, or was it the CoQ10 that produced the benefit? Will the improvement last? Shall we wait for Alzheimers advocates or the pharmaceutical industry to fund adequate trials of CoQ10? We should not hold our breath. CoQ10 is not patentable. When the traditional health care system fails us all we can do is take personal responsibility and act on our own behalf to the best of our ability.
Tuesday, July 17, 2007
medicine and exercise
#1
CTenaLouise
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Integrative medicine for PD - RX -supplementation and exercise
Parkinsons Patients - integrative medicine...Phosphatidylserine (PS), a phospholipid, is made by the body and is important to brain function. People with Parkinson's often have low levels of PS. One study showed that taking 100 mg of PS three times per day improved mood and brain function in people with Parkinson's. also in same article-Brahmi ( Bacopa monniera ) is an Ayurvedic herb that is often used to treat people with Parkinson’s. Studies have pointed to its effectiveness as an antioxidant for the brain and suggest that it improves circulation to the brain, as well as improving mood, cognitive function, and general neurological function. Dosage guidelines vary among practitioners, but 100 - 200 mg twice daily is often recommended.my 10 cents - a tiny /small even - op/ed on exercise~do not set unrealistic goals if you are considering a stationary bike in airconditioning... okay -ask your doc what he feels is safe...I like to walk, or lift hand waits - there are other ways of detoxification - other than sweating -loosing electrolytes are not a good idea, unless you have not had the PD beast long - less is more, you do not need to hurt yourselves ! okie dokie! becauseif I would have ever been able to ride a bike -I wouldnt have to worry about PD~ the reason being - is death!I was almost hit by a car AND - I crashed on a bicycle not built for 2!when I was 10 and my sister was 9! and she broke her arm... if you can do this after 10 to 15 years of PDyou are a miracle waiting to happen...
CTenaLouise
vbmenu_register("postmenu_124495", true);
Member
Join Date: Sep 2006
Location: MIDWEST, USA -
Posts: 707
Integrative medicine for PD - RX -supplementation and exercise
Parkinsons Patients - integrative medicine...Phosphatidylserine (PS), a phospholipid, is made by the body and is important to brain function. People with Parkinson's often have low levels of PS. One study showed that taking 100 mg of PS three times per day improved mood and brain function in people with Parkinson's. also in same article-Brahmi ( Bacopa monniera ) is an Ayurvedic herb that is often used to treat people with Parkinson’s. Studies have pointed to its effectiveness as an antioxidant for the brain and suggest that it improves circulation to the brain, as well as improving mood, cognitive function, and general neurological function. Dosage guidelines vary among practitioners, but 100 - 200 mg twice daily is often recommended.my 10 cents - a tiny /small even - op/ed on exercise~do not set unrealistic goals if you are considering a stationary bike in airconditioning... okay -ask your doc what he feels is safe...I like to walk, or lift hand waits - there are other ways of detoxification - other than sweating -loosing electrolytes are not a good idea, unless you have not had the PD beast long - less is more, you do not need to hurt yourselves ! okie dokie! becauseif I would have ever been able to ride a bike -I wouldnt have to worry about PD~ the reason being - is death!I was almost hit by a car AND - I crashed on a bicycle not built for 2!when I was 10 and my sister was 9! and she broke her arm... if you can do this after 10 to 15 years of PDyou are a miracle waiting to happen...
medicine and exercise
#1
CTenaLouise
vbmenu_register("postmenu_124495", true);
Member
Join Date: Sep 2006
Location: MIDWEST, USA -
Posts: 707
Integrative medicine for PD - RX -supplementation and exercise
Parkinsons Patients - integrative medicine...Phosphatidylserine (PS), a phospholipid, is made by the body and is important to brain function. People with Parkinson's often have low levels of PS. One study showed that taking 100 mg of PS three times per day improved mood and brain function in people with Parkinson's. also in same article-Brahmi ( Bacopa monniera ) is an Ayurvedic herb that is often used to treat people with Parkinson’s. Studies have pointed to its effectiveness as an antioxidant for the brain and suggest that it improves circulation to the brain, as well as improving mood, cognitive function, and general neurological function. Dosage guidelines vary among practitioners, but 100 - 200 mg twice daily is often recommended.my 10 cents - a tiny /small even - op/ed on exercise~do not set unrealistic goals if you are considering a stationary bike in airconditioning... okay -ask your doc what he feels is safe...I like to walk, or lift hand waits - there are other ways of detoxification - other than sweating -loosing electrolytes are not a good idea, unless you have not had the PD beast long - less is more, you do not need to hurt yourselves ! okie dokie! becauseif I would have ever been able to ride a bike -I wouldnt have to worry about PD~ the reason being - is death!I was almost hit by a car AND - I crashed on a bicycle not built for 2!when I was 10 and my sister was 9! and she broke her arm... if you can do this after 10 to 15 years of PDyou are a miracle waiting to happen...
CTenaLouise
vbmenu_register("postmenu_124495", true);
Member
Join Date: Sep 2006
Location: MIDWEST, USA -
Posts: 707
Integrative medicine for PD - RX -supplementation and exercise
Parkinsons Patients - integrative medicine...Phosphatidylserine (PS), a phospholipid, is made by the body and is important to brain function. People with Parkinson's often have low levels of PS. One study showed that taking 100 mg of PS three times per day improved mood and brain function in people with Parkinson's. also in same article-Brahmi ( Bacopa monniera ) is an Ayurvedic herb that is often used to treat people with Parkinson’s. Studies have pointed to its effectiveness as an antioxidant for the brain and suggest that it improves circulation to the brain, as well as improving mood, cognitive function, and general neurological function. Dosage guidelines vary among practitioners, but 100 - 200 mg twice daily is often recommended.my 10 cents - a tiny /small even - op/ed on exercise~do not set unrealistic goals if you are considering a stationary bike in airconditioning... okay -ask your doc what he feels is safe...I like to walk, or lift hand waits - there are other ways of detoxification - other than sweating -loosing electrolytes are not a good idea, unless you have not had the PD beast long - less is more, you do not need to hurt yourselves ! okie dokie! becauseif I would have ever been able to ride a bike -I wouldnt have to worry about PD~ the reason being - is death!I was almost hit by a car AND - I crashed on a bicycle not built for 2!when I was 10 and my sister was 9! and she broke her arm... if you can do this after 10 to 15 years of PDyou are a miracle waiting to happen...
Friday, July 13, 2007
.....there is hope
Hope for Parkinson's treatment
Nerve cell death leads to Parkinson'sScientists have discovered a protein which may help to slow, or even reverse symptoms of Parkinson's disease.
Parkinson's destroys nerve cells that produce the brain chemical dopamine, causing movement and balance problems.
Finnish researchers found the new molecule can prevent degeneration of these cells - and help damaged cells start to recover.
Their paper, featured in Nature, showed symptoms eased in rats given injections of the protein.
Our new protein has great potential to be developed as drug for Parkinson's disease
Dr Mart SaarmaUniversity of Helsinki
Current anti-Parkinson's drugs do not stop nerve cells from degenerating and dying, and their effects can be patchy and short-lived.
The researchers, from the University of Helsinki, believe the new molecule - dubbed conserved dopamine neurotrophic factor (CDNF) - has great potential as a treatment.
Previous research has centred on another protein - GDNF - which some research had suggested could improve symptoms in Parkinson's patients.
However, other studies have thrown doubt over the effect of the protein - and raised serious safety issues.
The Helsinki team decided to search for related proteins - known as growth factors - which worked in a similar way, but were likely to be better tolerated.
They found that CDNF, unlike other similar growth factors, was specific to brain nerve cells.
Experiments were carried out on rats bred to show symptoms similar to Parkinson's.
In tests, CDNF protected 96% of nerve cells in the brains of the animals from degeneration.
Delay in treatment
To test whether the protein could also help repair damage in nerve cells the researchers also waited a month before treating some of the animals to allow Parkinson's symptoms to really take hold.
This was designed to mimic the situation in human patients, who may already have lost 70% of their dopamine-producing nerve cells by the time they seek treatment.
Following treatment 58% of the dopamine-producing nerve cells were left alive, compared with just 26% in animals who did not receive the protein.
Lead researcher Dr Mart Saarma said: "Our new protein has great potential to be developed as drug for Parkinson's disease, but we need to do more animal experiments and also toxicology studies before we can start clinical trials."
Dr Kieran Breen, of the Parkinson's Disease Society, said the research was still at a very early stage.
"What is interesting is that the protein shows similar neuro-protective actions to GDNF which indicates that this general type of drug may be useful in the future for developing new therapies for treating Parkinson's.
"However, while GDNF showed some benefits in early clinical trials, larger trials showed side effects, which led to it being withdrawn. It is therefore too early to predict the therapeutic potential of CDNF."
Nerve cell death leads to Parkinson'sScientists have discovered a protein which may help to slow, or even reverse symptoms of Parkinson's disease.
Parkinson's destroys nerve cells that produce the brain chemical dopamine, causing movement and balance problems.
Finnish researchers found the new molecule can prevent degeneration of these cells - and help damaged cells start to recover.
Their paper, featured in Nature, showed symptoms eased in rats given injections of the protein.
Our new protein has great potential to be developed as drug for Parkinson's disease
Dr Mart SaarmaUniversity of Helsinki
Current anti-Parkinson's drugs do not stop nerve cells from degenerating and dying, and their effects can be patchy and short-lived.
The researchers, from the University of Helsinki, believe the new molecule - dubbed conserved dopamine neurotrophic factor (CDNF) - has great potential as a treatment.
Previous research has centred on another protein - GDNF - which some research had suggested could improve symptoms in Parkinson's patients.
However, other studies have thrown doubt over the effect of the protein - and raised serious safety issues.
The Helsinki team decided to search for related proteins - known as growth factors - which worked in a similar way, but were likely to be better tolerated.
They found that CDNF, unlike other similar growth factors, was specific to brain nerve cells.
Experiments were carried out on rats bred to show symptoms similar to Parkinson's.
In tests, CDNF protected 96% of nerve cells in the brains of the animals from degeneration.
Delay in treatment
To test whether the protein could also help repair damage in nerve cells the researchers also waited a month before treating some of the animals to allow Parkinson's symptoms to really take hold.
This was designed to mimic the situation in human patients, who may already have lost 70% of their dopamine-producing nerve cells by the time they seek treatment.
Following treatment 58% of the dopamine-producing nerve cells were left alive, compared with just 26% in animals who did not receive the protein.
Lead researcher Dr Mart Saarma said: "Our new protein has great potential to be developed as drug for Parkinson's disease, but we need to do more animal experiments and also toxicology studies before we can start clinical trials."
Dr Kieran Breen, of the Parkinson's Disease Society, said the research was still at a very early stage.
"What is interesting is that the protein shows similar neuro-protective actions to GDNF which indicates that this general type of drug may be useful in the future for developing new therapies for treating Parkinson's.
"However, while GDNF showed some benefits in early clinical trials, larger trials showed side effects, which led to it being withdrawn. It is therefore too early to predict the therapeutic potential of CDNF."
Sunday, July 1, 2007
a son's advice to PD effected father
Abu,Allah will give you sabar and all of us strength to help you through this.The race is just at the starting point. the rest of the pit crew isprimed but first you need to start the engine for a successful journey.As in the article also you would notice the twice a week workout he isdoing... you need to also make more of an effort to get some regularexercise done even something simple as a regular walk in hilal park.Everyone gets up for Fajar... maybe that is when you should step outwith Mama for the walk rather than after work when one is naturallytired.you have faced and overcome so many challenges in your life (eg:selling financial / travel services / banking after a life of sellingcigarettes but having study some sort of HISTORY !!!) so another oneshould not really bother you... approach it as you have done the pastchallenges... understand the challenge and take steady action.Yes things MAY slowly become worse but remember, if you leave all yourdoors and windows open, the dust will just fly in ....... but the dustfinds it much harder to get into the house if the doors and windows areclosed and the house is regularly cleaned. You dont need to go andleave all the doors and windows open Abu....... CLOSE them...... andclean the house.......
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